AMROSE: AMsterdam ROtterdam SEdation research

AMROSE: AMsterdam ROtterdam SEdation research

In 2005, the Royal Dutch Medical Association (RDMA) launched the national palliative sedation guideline. In this guideline palliative sedation is defined as ‘the intentional lowering of consciousness of a patient in the last phase of life’ This refers to all subtypes of sedation; intermittent and continuous as well as deep and superficial. In 2005, in a nationwide study showed a frequency of continuous deep sedation until death of 8.2%.
Goal of the AMROSE-study is to describe the practice of palliative sedation and to establish to what extent this practice is in accordance with the RDMA-guideline. For that purpose physicians and nurses were asked to fill out questionnaires and some of them were additionally interviewed. Also, sedated patients were monitored to establish which instruments can be used to measure depth of sedation and the severity of symptoms.
The questionnaire study amongst physicians and nurses took place in 2008 and the subsequent interviews in 2008 en 2009. In this part of our research project  we focussed on one specific form of palliative sedation, described in the national guideline, namely: continuous sedation until death. The inclusion for the monitoring study took place from 2008-2010. In this part of the research patients receiving continuous sedation as well as intermittent sedation were included.

In the AMROSE-project researchers participate from both the Erasmus MC in Rotterdam and the VUmc in Amsterdam.

For information: S.J. (Siebe) Swart, MD