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S.L.W. (Stijn) Koolen

KoolenPosition:  Ziekenhuisapotheker, klinisch farmacoloog

Main activities: Stijn Koolen studied pharmaceutical sciences at the Utrecht University and obtained his PharmD degree in 2006. In that year he started with a PhD  training at the Netherlands Cancer Institute (NKI) Amsterdam.

Focus of research:
His research focused on the clinical development of orally administered anti-cancer drugs. During his PhD he followed a clinical training to become a Clinical pharmacologist. He defended his thesis  “Intravenous to oral switch in anticancer chemotherapy – focus on taxanes and gemcitabine” in 2011.

In 2011 he started with a four year specialization phase at the Spaarne Gasthuis  Haarlem to become  a hospital pharmacist. Further specialization in pediatric pharmacology and oncology were done during internships at the Amsterdam Medical Center and Erasmus Medical Center.  

Since 2015, Stijn has been a post-doctoral fellow at the laboratory of translational pharmacology at the department of Medical oncology and a hospital pharmacist at the department of pharmacy. His main research is focused on the relationship between pharmacokinetics of oncology drugs and toxicity or response. A better understanding  of this relationship may lead to a better and more personalized treatment for many oncology drugs. An example is pharmacokinetically guided dosing (TDM), which is adjusting the administered dose based on the measured drug concentration in blood. TDM is also one of his focus areas in clinical patient care.  Furthermore, Stijn is involved in the compounding and quality control of radiopharmaceuticals and is a member of the medical ethics committee of the Erasmus medical center.

Publicaties Stijn Koolen 

Stijn Koolen Linkedin profiel